What is CBD Oil? What is Cannabidiol? (can·na·bi·di·ol)

Cannabidiol (CBD) is the 2nd most prevalent cannabinoids found in the cannabis plant, and it is emerging as a promising therapy for many illnesses that experts have previously considered to be untreatable, including:

• Pain (neuropathic, chronic, cancer-related, etc.)
• Epilepsy
• Multiple Sclerosis (MS)
• Amyotrophic Lateral Sclerosis (ALS)
• Parkinson’s
• Inflammation
• Acne
• Dyskinesia
• Psoriasis
• Broken Bones
• Mad Cow Disease
• Depression
• Bacterial Infections
• Diabetes
• Rheumatoid Arthritis
• Nausea
• Anxiety
• ADHD
• Schizophrenia
• Substance Abuse/Withdrawal
• Heart Disease
• Irritable Bowel Syndrome (IBS)

Although there are many cannabinoids, CBD and tetrahydrocannabinol (THC) are the two people are most familiar with. THC exists in large quantities in cannabis plants – it’s the cannabinoid that’s responsible for most of the psychoactive effects that cause cannabis users to get, and feel, “high.”

Cannabidiol also is found in cannabis plants, but usually at much lower levels, unless the cultivar has been bred for a high CBD content. The primary source of most CBD on the market today is from the agricultural hemp plant. Over  10,000 years ago, hemp was one of the first plants spun into fiber and it is also one of the fastest growing plants in the world.

People often grow hemp for food, clothing, building/plastic composite materials, jewelry, animal bedding, biofuel, weed control, water/soil purification, paper, and more.

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Antagonizing GPR55 Receptors: GPR55 receptors are widely distributed in the brain (especially the cerebellum) and help control bone density and blood pressure. Additionally, GPR55 promotes cancer cell proliferation when activated. These facts may explain CBD’s therapeutic role in osteoporosis and high blood pressure. [S]

Activating TRPV1 Receptors: Involved in regulating pain, body temperature, and inflammation) [other substances targeting TRPV1 receptors include anandamide, AM404 (a metabolite of acetaminophen), capsaicin, and various cannabinoids such as CBN, CBG, CBC, THCV, and CBDV.

Activating the 5-ht1A Receptor (at high doses): The 5-ht1a receptor helps regulate anxiety, addiction, appetite, sleep, pain perception, nausea, and vomiting. CBDA (the raw form of CBD) shows an even higher affinity for this receptor than CBD. [S]

Activating PPAR-gamma Receptors: PPAR-gamma receptors are located on the cell’s nuclei and play a role in degrading beta-amyloid plaque, as well as lipid uptake, insulin sensitivity, and dopamine release. This action explains why CBD may benefit diabetes, schizophrenia, and Alzheimer’s. [S]

Credit: https://cbdoilreview.org/cbd-cannabidiol/what-is-cbd-oil/